ACEL,Inc. is CRO of Cell-based Assays.

Test Outline

PerkinElmer's（Revvity's） Operetta CLS and Opera Phenix Plus are used for testing.


　 　　　　　　　 Operetta CLS


　 　　　　　　　 Opera Phenix Plus


Quantitative data analysis of adherent cells can be performed.
It differs from ordinary fluorescence microscopes in its unparalleled image-analyzing capability and ability to screen multiple samples.

High Content Imaging (HCI) is also known as High Content Screening (HCS) or High Content Analysis (HCA).

In many tests, a sample is added to the cells.
The cells are then fluorescently stained, both with and without the sample added to the cells.

By analyzing the fluorescent images of the cells, the effect of the sample on the cells can be quantitatively and numerically determined.
It can be the morphology of the cell or the localization of proteins within the cell.

Cells come in many different types.
Cells in each tissue maintain their own unique properties.

These things allow us to determine how a sample will affect an organism (mainly humans) at the cellular level, using a variety of parameters.

Features of Operetta CLS and Opera Phenix Plus

The most important feature of the Operetta CLS and the Opera Phenix Plus is the excellence of the image analysis software called Harmony.

It accurately recognizes each individual cell.
It also accurately recognizes intracellular proteins.

Another feature is the ease of use of the image analysis software.
Typical image analysis applications are installed in advance.
In addition, image analysis methods specific to each test can be easily programmed.

These allow cell images to be presented as scientifically objective and well-founded numerical values.
By presenting fluorescent images, which at first glance may seem to be a subjective judgment, as objective numerical values, it is possible to obtain scientifically grounded data.

Optical Path

Operetta　CLS




Opera Phenix Plus